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Ischaemic heart disease, hypertension and heart failure in anaesthesia

In a patient with ischaemic heart disease the aim is to keep the balance between myocardial oxygen supply and demand: a slow heart rate, a good diastolic pressure, no pain, cold or severe anaemia; and in a patient with hypertension or heart failure — to keep blood pressure stable and not depress the heart.

Why it matters in the exam

The exam asks about detecting ischaemia during surgery (lead V5 and lead II), treating ischaemia during surgery, continuing beta blockers and statins, the POISE trial and the danger of starting a high-dose beta blocker on the day of surgery, myocardial injury after surgery (MINS) and troponin measurement, the blood pressure values that postpone surgery, and the effect of a mean pressure below 65 on the kidneys and heart.

Ischaemia during surgery usually appears without pain, as an ST-segment change, a fall in pressure, an arrhythmia or a wall-motion change on transoesophageal echo. Lead V5 detects most events, and adding lead II improves detection. Treatment: check oxygenation and haemoglobin, slow tachycardia with a beta blocker, correct hypotension with a vasoconstrictor, give nitroglycerin only if blood pressure allows, deepen anaesthesia and relieve pain. If there is persistent ST elevation — consult a cardiologist about catheterisation, weighing the bleeding risk from surgery. The POISE trial from 2008 showed that starting a high-dose beta blocker close to surgery reduced heart attacks but raised stroke and death; so a beta blocker is continued in those already taking one, and not started at high dose on the day of surgery.

Under the ESC guidelines from 2022, in high-risk patients troponin is measured before major surgery and 24 and 48 hours after it, because most myocardial injuries after surgery are silent and linked to death. After elective stent placement, non-urgent surgery is usually postponed for at least 6 months, and after an acute coronary syndrome 12 months. In hypertension, elective surgery is usually postponed if the pressure is 180/110 or higher; lower values are not a reason to postpone. During surgery a mean pressure above about 65 is kept, because prolonged hypotension is linked to kidney and heart injury. In heart failure with reduced function, fluids are balanced carefully, strong myocardial depression is avoided, and arterial monitoring and high-dependency admission are planned.

Key points

Summary table

ConditionManagementExam point
Ischaemia during surgeryOxygen, haemoglobin, slow the heart rate, correct pressure, nitroglycerin if pressure allowsUsually painless; V5 detects most events
Beta blockerContinue if the patient takes it; do not start at high dose on the day of surgeryPOISE 2008: more stroke and death
Troponin after surgeryHigh risk: before, and 24 and 48 hours afterMINS is usually silent
StentPostpone elective surgery 6 months after elective stenting, 12 after an acute eventDo not stop aspirin in most patients
HypertensionPostpone elective surgery if 180/110 or higherIn surgery keep the mean pressure above 65
Heart failureFluids with care, avoid depression, arterial monitoringLook for signs of decompensation before surgery

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Sources

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Reviewed by the Examqo AI Professor · 2026-11-02. The text may contain errors; when in doubt, check the source.