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Obstetric anaesthesia

Pregnancy reduces the oxygen reserve, raises the risk of aspiration and of a difficult airway and compresses the vena cava — so spinal anaesthesia is preferred for caesarean section and general anaesthesia is kept for emergencies.

Why it matters in the exam

The exam asks about the physiological changes of pregnancy and their meaning for anaesthesia, why regional anaesthesia is preferred for caesarean section, the treatment of hypotension after spinal anaesthesia (phenylephrine), the platelet count that allows a block in pre-eclampsia, and the drugs for postpartum haemorrhage and their contraindications. Other questions deal with labour epidural — does it raise the caesarean section rate (no).

In pregnancy the FRC falls by about 20% and oxygen consumption rises, so desaturation during apnoea is fast; the airway mucosa is oedematous, and the lower oesophageal sphincter is weak. From about week 20 the uterus compresses the inferior vena cava when supine — so the uterus is displaced to the left. MAC falls and sensitivity to local anaesthetics rises. For general anaesthesia at caesarean section an RSI is done with a smaller tube and preparation for a difficult airway.

Remember that obstetric anaesthesia has two patients: every decision is judged also by its effect on the fetus — uterine blood flow depends on maternal blood pressure, so hypotension is treated quickly. A labour epidural gives good analgesia and allows quick extension for an urgent caesarean section, so it is recommended to offer it early to women at risk of surgery or of a difficult airway. In exam questions, caesarean section under general anaesthesia is the right answer mainly when there is no time or when a block is contraindicated.

Key points

Summary table

IssueWhat is doneExam point
Hypotension after spinalPhenylephrine as first line (prophylactic infusion), with fluidsEphedrine causes more fetal acidosis
Aortocaval compressionLeft uterine displacementFrom about week 20
Pre-eclampsiaA neuraxial block is allowed with platelets of 70,000 or more and no other risk factorMagnesium prolongs muscle relaxants
Postpartum haemorrhageOxytocin slowly; carboprost; methylergometrine; tranexamic acid 1 gCarboprost forbidden in asthma; methylergometrine forbidden in hypertension
Aspiration prophylaxisSodium citrate, H2 blocker, metoclopramideIn general anaesthesia — RSI

In the full version for subscribers

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Sources

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Reviewed by the Examqo AI Professor · 2026-11-02. The text may contain errors; when in doubt, check the source.