Examqo

Examqo › Examqo library › Ophthalmology › Neuro-ophthalmology · IMLE

Visual pathway and localisation of field defects

The shape of the field defect reveals where the damage is: before the chiasm the defect is in one eye, at the chiasm it is bitemporal, and behind it it is homonymous — and the more posterior the lesion, the more congruous the defect between the two eyes.

Why it matters in the exam

Exams love localisation questions. Optic nerve: a defect in one eye — central, altitudinal or arcuate — with an RAPD. Junctional scotoma: a central defect in one eye with a superotemporal defect in the other — a lesion where the optic nerve joins the chiasm. Chiasm: bitemporal hemianopia; a pituitary adenoma presses from below so the defect starts in the superotemporal quadrants, and a craniopharyngioma presses from above and starts in the inferior quadrants. Pituitary apoplexy — sudden headache, reduced vision and cranial nerve palsies — is an emergency.

Behind the chiasm: optic tract — incongruous homonymous hemianopia with an RAPD in the eye contralateral to the lesion (the eye that lost the larger temporal field). Meyer loop in the temporal lobe — superior homonymous quadrantanopia ("pie in the sky"). Parietal lobe — inferior quadrantanopia ("pie on the floor"). Occipital cortex — highly congruous homonymous hemianopia, usually with macular sparing because of dual blood supply from the PCA and MCA; the usual cause is a PCA stroke. Bilateral occipital damage causes cortical blindness with normal pupils, and sometimes denial (Anton syndrome).

Tests: confrontation fields for screening, Humphrey 24-2 or 30-2 for the central field and 10-2 for defects near fixation, Goldmann for the peripheral field. Any new homonymous hemianopia requires brain imaging, and any bitemporal defect — pituitary MRI and hormonal tests. A significant homonymous hemianopia usually precludes driving. Remember that a patient with hemianopia often complains of "poor vision in one eye" — usually the eye that lost the temporal field — so both eyes are always tested separately.

Key points

Summary table

LocationDefectTypical cause
Optic nerveOne-eye defect, RAPDInflammation, ischaemia, compression
Optic nerve–chiasm junctionJunctional scotomaMeningioma
ChiasmBitemporal hemianopiaPituitary adenoma, craniopharyngioma
Optic tractIncongruous hemianopia, contralateral RAPDTumour, demyelination
Meyer loopSuperior homonymous quadrantanopiaTemporal lobe stroke or tumour
Occipital cortexCongruous hemianopia with macular sparingPCA stroke

In the full version for subscribers

The full version is open to subscribers of: Ophthalmology, Medical licensing exam (IMLE), Neurology.

Subscriber? Read the full topic Plans and prices 25 free questions

Sources

Sources are given for further reading; the text is written afresh and not copied from them.

Reviewed by the Examqo AI Professor · 2026-11-06. The text may contain errors; when in doubt, check the source.