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Acne and rosacea

Acne is treated in steps by lesion type and severity — a topical retinoid and benzoyl peroxide for all, oral antibiotics for moderate, and isotretinoin for severe or scarring acne; rosacea looks similar but has no comedones and is treated differently.

Why it matters in the exam

The exam presents an adolescent with mild acne and asks for the first treatment, a girl who has not improved after a month of benzoyl peroxide (too early to judge), and a patient starting isotretinoin with questions about contraception and tests. For rosacea it asks the topical treatment and what is forbidden.

Remember that a topical or oral antibiotic is always given with benzoyl peroxide to prevent resistance, and that oral antibiotics are limited to 3–4 months.

Acne strongly affects adolescents' self-image, so even "mild" acne deserves full treatment and an explanation of how long it takes to see improvement.

Questions on isotretinoin test pregnancy prevention, blood tests before and during treatment, and asking about the patient's mood. Acne appearing suddenly in an adult woman with hirsutism and irregular periods requires a hormonal work-up. It is also worth asking about drugs that worsen acne, such as steroids, lithium and progestogen products.

Key points

Summary table

ConditionFindingTreatmentExam note
Mild comedonal acneBlackheads and whiteheadsTopical retinoid (adapalene, tretinoin)Improvement is seen after 8–12 weeks
Mild inflammatory acneFew papules and pustulesBenzoyl peroxide and a topical retinoid, with topical clindamycin if neededA topical antibiotic never alone
Moderate acneMany papules, back lesionsOral doxycycline with topical treatmentLimit to 3–4 months
Severe, nodular or scarring acneNodules, scars, treatment failureIsotretinoin 0.5–1 mg/kg a dayTeratogenic: two contraceptive methods and monthly pregnancy tests; liver tests and lipids
Hormonal acne in a womanJaw and chin, premenstrual flareCombined pill or spironolactoneLook for signs of androgen excess (PCOS)
RosaceaCentral facial redness, flushing, papules without comedonesTopical metronidazole, azelaic acid or ivermectin; low-dose doxycyclineAvoid topical steroids and flushing triggers

A free exam question

( מהו סיבוך אפשרי של טיפול לאקנה Acne ? ) בתכשיר פומי מקבוצת הרטינואידים (the question as examined, in Hebrew)

  1. א. היפרגליקמיה בצום
  2. ב. פיברוזיס של הכבד
  3. ג. מחלה ציסטית של הכליה
  4. ד. פסאודו-טומור צרברי

See the answer and explanation

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Sources

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Reviewed by the Examqo AI Professor · 2026-11-06. The text may contain errors; when in doubt, check the source.