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Active stone treatment: SWL, URS and PCNL

The stone treatment is chosen by size, site, density and anatomy — an uncomplicated ureteral stone up to 10 mm gets a trial of medical expulsive therapy (MET), a renal stone up to 2 cm is treated with SWL or flexible ureteroscopy (RIRS), and a renal stone over 2 cm is treated with PCNL.

Why it matters in the exam

Exam questions are built on a case with a stone of a given size and site, and the correct answer is the first treatment the guideline recommends. A stone up to 5 mm usually passes on its own; a distal ureteral stone over 5 mm and up to 10 mm gets an alpha-blocker (tamsulosin 0.4 mg once daily) for up to 4 to 6 weeks, provided there is no infection, no uncontrolled pain and no loss of renal function. Ureteroscopy (URS) is the preferred active treatment for most ureteral stones, and SWL is an alternative for an upper ureteral stone up to 10 mm.

SWL success drops when stone density is above 1000 Hounsfield units, when the skin-to-stone distance is over 10 cm, with cystine stones, and with a lower-pole stone with a steep infundibulopelvic angle, an infundibulum narrower than 5 mm or a calyx longer than 10 mm. Contraindications to SWL: pregnancy, a bleeding disorder or anticoagulants that were not stopped, an untreated urinary infection, obstruction below the stone and an arterial aneurysm close to the stone. After SWL a "stone street" (Steinstrasse) may form — a column of fragments that blocks the ureter.

Uric acid stones are radiolucent and can be dissolved by alkalinising the urine with potassium citrate to a pH of 7.0 to 7.2. Before any active treatment a urine culture is mandatory and infection must be treated. In pregnancy — ultrasound first, and if drainage is needed: a JJ stent or a nephrostomy; ureteroscopy is possible, SWL is forbidden. In PCNL an access above the 12th rib carries a risk of pleural injury.

Key points

Summary table

SituationFirst treatmentAlternativeNote
Distal ureteral stone 5 to 10 mm, uncomplicatedMET with tamsulosinURSFollow-up for up to 4 to 6 weeks
Ureteral stone that needs removalURSSWL for an upper stone up to 10 mmURS gives more stone-free results in one session
Renal stone up to 2 cmSWL or RIRSPCNLLower pole with unfavourable anatomy — RIRS or PCNL
Renal stone over 2 cm or staghornPCNLStaged RIRSAccess through a posterior calyx
Uric acid stoneDissolution with potassium citrateURSUrine pH 7.0 to 7.2
PregnancyDrainage with a stent or nephrostomyURSSWL and standard CT are avoided

A free exam question

מהם התנאים הדרושים ליצירת אבני חומצה אורית? (the question as examined, in Hebrew)

  1. א. שתן חומצי, היפראורצמיה, נפח שתן גבוה
  2. ב. שתן חומצי, היפראוריקוזוריה, נפח שתן נמוך
  3. ג. שתן בסיסי, היפראורצמיה, נפח שתן נמוך
  4. ד. שתן בסיסי, היפראוריקוזוריה, נפח שתן נמוך

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Sources

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Reviewed by the Examqo AI Professor · 2026-11-06. The text may contain errors; when in doubt, check the source.