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Medical complications after stroke

After stroke, complications such as shoulder pain, depression, aspiration, venous thrombosis and falls hold back rehabilitation as much as the weakness itself — so they are looked for systematically and prevented from day one.

Why it matters in the exam

The exam asks about causes and treatment of hemiplegic shoulder pain, prevention of venous thrombosis, swallow screening, depression, seizures and central pain. Hemiplegic shoulder pain is very common; causes include subluxation in the flaccid stage, spasticity, frozen shoulder, tendon injury and CRPS. Prevention includes correct positioning and support of the arm, avoiding pulling on the arm and avoiding overhead pulley exercises; treatment includes botulinum injections into spastic muscles, a suprascapular nerve block and electrical stimulation of the shoulder muscles for subluxation.

Venous thrombosis: in a patient who is not walking, intermittent pneumatic compression of the legs (the CLOTS 3 trial) reduced thrombosis, and compression stockings alone are not recommended; prophylactic heparin is given according to bleeding risk. Swallowing: a screening test before any food or drugs by mouth, and with suspected aspiration — clinical assessment and an instrumental study. Post-stroke depression occurs in about a third of patients, holds back rehabilitation and is treated with talking therapy and drugs (usually an SSRI). Seizures can occur, but anti-seizure drugs are not given prophylactically.

Central post-stroke pain (Dejerine-Roussy syndrome) usually follows a thalamic lesion: burning pain on the affected side with hypersensitivity to touch and cold, treated with drugs for neuropathic pain (amitriptyline, lamotrigine, pregabalin). Other complications: urinary incontinence (usually an uninhibited bladder), falls and fractures on the paretic side (disuse osteoporosis), pressure injuries, fatigue, spasticity and return to driving — which needs assessment of vision, attention and judgement.

Key points

Summary table

ComplicationCluesPrevention and treatment
Hemiplegic shoulder painPain on movement, subluxation, spasticityPositioning and support; no overhead pulley; botulinum, suprascapular nerve block
Venous thrombosisPatient not walkingIntermittent pneumatic compression; heparin by risk
Aspiration and pneumoniaCoughing when eating, "wet" voiceSwallow screen before food by mouth
DepressionLow motivation, tearfulness, poor engagementRoutine screening, talking therapy and an SSRI
Central (thalamic) painBurning pain and hypersensitivity on the affected sideAmitriptyline, lamotrigine, pregabalin

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Sources

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Reviewed by the Examqo AI Professor · 2026-11-06. The text may contain errors; when in doubt, check the source.