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Cleft lip and palate

Cleft lip results from failed fusion of the medial nasal prominence with the maxillary prominence, and cleft palate from failed fusion of the palatal shelves; treatment is a timed sequence of operations by a team — lip at about 3 months, palate at 9 to 18 months, alveolar bone graft at 7 to 11 years and jaw surgery after growth ends.

Why it matters in the exam

Cleft lip with or without cleft palate occurs in about 1 in 700 to 1,000 births, more in boys and more on the left; isolated cleft palate is less common, more in girls and more often syndromic — 22q11, Stickler and Van der Woude (IRF6, lower lip pits). Most bilateral cleft lips are accompanied by cleft palate. The primary palate lies in front of the incisive foramen and the secondary palate behind it. Lip repair (Millard — rotation-advancement, or Fisher — anatomical subunits) is done around 3 months; palate repair is done before speech develops, repositioning the levator veli palatini muscle transversely (intravelar veloplasty) or using Furlow's double-opposing Z-plasty. The main aim of the alveolar bone graft is bony support for eruption of the permanent canine, arch stabilisation and fistula closure — so it is done before the canine erupts.

Velopharyngeal insufficiency (VPI) remains in about 20 to 30% after palate repair and presents with hypernasal speech and nasal air escape. Assessment is by nasendoscopy or videofluoroscopy; treatment: secondary Furlow, a pharyngeal flap when there is a central gap and good lateral wall motion, or sphincter pharyngoplasty when the gap is lateral and wall motion is weak. Submucous cleft palate is recognised by a triad: bifid uvula, a translucent midline band in the soft palate and a notch in the posterior hard palate. Pierre Robin — small jaw, tongue retraction and airway obstruction, usually with a U-shaped cleft palate — is managed with prone positioning, a nasopharyngeal airway, and in severe cases mandibular distraction; Stickler syndrome should be sought (eye examination). Middle ear infections are common and need follow-up and sometimes tubes.

Key points

Summary table

StageAgeAimNote
Lip repairAbout 3 monthsClosure, muscle and nose reconstructionMillard or Fisher
Palate repair9 to 18 monthsNormal speech, levator reconstructionFurlow or intravelar veloplasty
VPI treatmentAfter speech assessmentClose the velopharyngeal gapPharyngeal flap — central gap; sphincter — lateral gap
Alveolar bone graft7 to 11 yearsSupport for canine eruption, stabilisation, fistula closureBefore the canine erupts
Jaw surgeryAfter growth endsJaw relationshipMidface hypoplasia

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Sources

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Reviewed by the Examqo AI Professor · 2026-11-06. The text may contain errors; when in doubt, check the source.